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Automatic mixing

Ensuring homogenous blood gas samples

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Achieve trusted tHb blood gas results with automatic mixing

Automatic mixing is a unique way of mixing blood gas samples prior to analysis that ensures a homogeneous sample, enabling more accurate hemoglobin results.

Automatic mixing functions exclusively with Radiometer analyzers featuring an inbuilt automatic safePICO mixer, in combination with safePICO syringes.

Doctor and nurse checking results. ABL90 FLEX blood gas analyzer in the backgroundDoctor and nurse checking results. ABL90 FLEX blood gas analyzer in the background

Reduce preanalytical errors with automatic mixing

Studies show the preanalytical phase of blood gas testing to be the phase most prone to errors.

Automatic mixing helps you mitigate preanalytical errors – such as insufficient mixing – by removing many of the operator-related variables that may lead to non-homogeneous samples.

Radiometer's automatic mixing solution does not cause hemolysis.

Optimize your blood gas workflow

Studies show that manual mixing may causes random bias. Automatic mixing may minimize unnecessary testing while ensuring homogeneous samples and enabling accurate hemoglobin results; a cornerstone of costly decisions around red blood cell transfusions (RBCT) [1] (see Figure 1).


Automatic mixing is efficient, with samples mixed in approximately eight seconds (ABL90 and ABL800). In comparison, current recommendations from the CLSI (Clinical Laboratory Standards Institute) for manual mixing, are to gently mix the sample for a minimum of one minute.



Figure 1. Bland-Altman plots. Bland-Altman plots of agreement in the measurement of hemoglobin given by the ABL90 FLEX for manual (A) versus automatic mixing (B) in reference to Sysmex. Hospital color coding: Adventist Bolingbrook, (Green); Adventist GlenOaks (Blue); Adventist Hinsdale (Bordeaux); Adventist LaGrange (Red); University of Minnesota (Yellow). The main difference (solid line) and the CLIA allowable total error acceptability limits for hemoglobin of 4% (dotted lines) are shown. [1]

Optimize your blood gas workflow

Studies show that manual mixing may causes random bias. Automatic mixing may minimize unnecessary testing while ensuring homogeneous samples and enabling accurate hemoglobin results; a cornerstone of costly decisions around red blood cell transfusions (RBCT) [1] (see Figure 1).


Automatic mixing is efficient, with samples mixed in approximately eight seconds (ABL90 and ABL800). In comparison, current recommendations from the CLSI (Clinical Laboratory Standards Institute) for manual mixing, are to gently mix the sample for a minimum of one minute.



Figure 1. Bland-Altman plots. Bland-Altman plots of agreement in the measurement of hemoglobin given by the ABL90 FLEX for manual (A) versus automatic mixing (B) in reference to Sysmex. Hospital color coding: Adventist Bolingbrook, (Green); Adventist GlenOaks (Blue); Adventist Hinsdale (Bordeaux); Adventist LaGrange (Red); University of Minnesota (Yellow). The main difference (solid line) and the CLIA allowable total error acceptability limits for hemoglobin of 4% (dotted lines) are shown. [1]

safePICO syringes are designed for automatic mixing

Each safePICO syringe contains a mixing ball. When placed in an automatic safePICO mixer, the magnetic part of the mixer will rotate the mixing ball, thus facilitating the mixing of blood samples.

safePICO self-fill and safePICO Aspirator

Above: safePICO self-fill and safePICO Aspirator.

Explorer our products and solutions

Blood gas syringes and capillary tubes

Radiometer capillary tubes, aspirating and self-fill blood gas syringes are designed with various features that are intended to reduce the risk of preanalytical errors.

1st Automatic

Pre-barcoded syringes help ensure correct patient-sample identification every time when using with a Radiometer blood gas analyzer with 1st Automatic.

Blood gas testing

Radiometer offers a flexible blood gas diagnostic solution that can fit seamlessly into your acute care testing and hospital workflow.

Related knowledge sources

Preanalytical blood gas errors

This handbook focuses on the preanalytical phase of blood gas testing and what you can do to minimize errors.

Patient blood management

Patient Blood Management is an evidence-based approach to optimizing the care of patients’ blood. This includes opportunities to minimize blood loss and avoid the inappropriate use of blood.

How-to videos - guide to blood gas

Watch six educational videos to support you in understanding blood gas analysis.

References

1. Altawallbeh, G.; Castaneda, P.; Wennecke, G.; Karger, A. B. (2020): Evaluation of automatic mixing versus manual mixing for point of care hemoglobin measurement. In Pract Lab Med 20, e00163. DOI: 10.1016/j.plabm.2020.e00163.

MAPSSS-000955 R1

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Effective Date January 20th, 2023 (last updated January 20th, 2023)

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