The Radiometer ABL800 FLEX blood gas analyzer demonstrated the best correlation to plasma creatinine and the best clinical concordance when creatinine values were used to calculate eGFR according to a recent study done by the Department of Laboratory Medicine and Pathology of world-renowned Mayo Clinic in the US.

 

The 266-patient study evaluated the clinical concordance of eGFR calculation using three whole blood creatinine methods compared to a reference plasma creatinine assay. In addition to Radiometer’s ABL800 FLEX blood gas analyzer, the Roche Integra 400, i-STAT and StatSensor participated in the study. According to the data, the Radiometer method exhibited both the smallest absolute bias between whole blood and plasma creatinine and the best overall concordance with plasma eGFR (93%).

 

 

Estimated Glomerular Filtration Rate (eGFR) is recognized to have great importance in the early detection and management of chronic kidney disease. The eGFR indicates how effectively the kidneys clear out the substrates from the body. Besides creatinine, the eGFR algorithm is based on age, gender and race.

 

Because mild and moderate kidney injury is poorly inferred from serum creatinine alone, The National Kidney Disease Education Program (NKDEP) “strongly encourages clinical laboratories to automatically report eGFR when serum creatinine is reported”. The purpose of NKDEP is to reduce the morbidity and mortality caused by kidney disease and its complications.

 

The ABL800 FLEX eGFR algorithm meets the NKDEP requirements and reports eGFR following the Modification of Diet in Renal Disease (MDRD) Study equation.

 

To find out more about the ABL800 FLEX’s outstanding creatinine measurements for the point-of-care.

 

 

Radiometer is a world leader in the development, manufacturing and distribution of techno-logically advanced acute care testing solutions.

 

Radiometer’s products and services simplify and automate all phases of acute care testing, so hospitals can get fast results, reduce their workload and the risk of errors, and improve cost effectiveness.